Nā Pahu ʻIke Carbapenemases ʻOki -Edge

CRE, i hōʻike ʻia mekiʻekiʻe o ka pilikia o ka maʻi, kiʻekiʻe o ka make, kiʻekiʻe o ke kumukūʻai a me ka paʻakikīi ka mālama ʻana, kāhea aku i kahika ʻike wikiwiki, kūpono a pololei hoʻinā ʻano hana e kōkua ai i ka ʻike ʻana a me ka hoʻokele lapaʻau.

Wahi a ke aʻo ʻana o nā ʻoihana kiʻekiʻe a me nā haukapila, ʻo Rapid Carbapenemases Detection Kit (Colloidal Gold) mai Macro & Micro -Test, e like me ka multi-qPCR assay, hāʻawi i ka pololei 100% kūpono i ka ʻike ʻana i nā carbapenemases i nā isolates bacteria. ʻOi aku kēia hana koʻikoʻi ma mua o nā ʻano phenotypic kuʻuna e like me mCIM/eCIM a me CDT. ʻO ka mea nui, hōʻike nā assays gula colloidal i ka 100% sensitivity, specificity, positive predictive value, a me ka maikaʻi ʻole predictive value no kēlā me kēia carbapenemase i hoʻāʻo ʻia, e hōʻike ana i kā lākou hana kūikawā a kūlike i ka ʻike ʻana i nā bacteria e hana ana i ka carbapenemase.

Koho 1:

WikiwikiPahu ʻIke Carbapenemases (Colloidal Gold), kahi holomua holomua e hoʻoponopono ai i ka pilikia wikiwiki o CRE e hoʻoweliweli nei i ke olakino lehulehu honua, 1-2 mau lā ma mua o ke ʻano o ka maʻalahi o ka lāʻau lapaʻau;

 15 mau minukee ʻike wale iā NDM, KPC, OXA-48, IMP a me VIM i hoʻokahi hoʻāʻo;

 Hana maʻalahi e ka wai moʻomeheu koko me ka ʻole o ka moʻomeheu pā, 10 mau minuke wale no ka lysis a me ka holoi ʻana;

 ʻO ke ʻano kiʻekiʻe a ʻaʻohe cross-reactivity me nā bacteria pathogenic maʻamau e like me Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa a i ʻole nā ​​​​​​laʻana hana β-lactamase ʻē aʻe;

 Ka Hoʻohana Laulā: Nā ʻano hiʻohiʻona like ʻole e pili ana i nā haukapila, nā keʻena lapaʻau, a me nā kikowaena olakino kaiāulu.

Koho 2:

Pahu ʻIke Gene Kūʻē Carbapenem (Fluorescence PCR), Hoʻāʻo 6-i-1me ka hopena i loko40 mau minuke, kuhikuhi pololeiNDM, KPC, OXA23, OXA-48, IMP a me VIMma hoʻokahi hoʻāʻo;

 Laʻana maʻalahi: Sputum, rectal swab a i ʻole nā ​​kolone maʻemaʻe;

 Hoʻemi ʻia ke kumukūʻai: 6 mau pahuhopu i ʻike ʻia e 1 hoʻāʻo hoʻokahi e pale aku i nā hoʻāʻo hou;

 ʻIke Kiʻekiʻe a me ke Kikoʻī: 1000CFU/mL no ka ʻike a ʻaʻohe cross-reactivity me nā pathogens hanu ʻē aʻe a i ʻole nā ​​​​​​laʻana e loaʻa ana nā genes pale lāʻau ʻē aʻe CTX, mecA, SME, SHV, TEM, etc.;

 Hoʻohālikelike ākea: Me nā mea hana PCR maʻamau;