Laʻana-i-Pane C. ʻIke ʻokoʻa ʻokoʻa

He aha ke kumu o ka maʻi C. Diff?

ʻO ka maʻi C.Diff ma muli o ka hua bacteria i kapa ʻia ʻoClostridioides difficile (C. difficile), ka mea maʻamau e noho pōʻino ʻole i loko o ka ʻōpū. Eia nō naʻe, ke hoʻopilikia ʻia ke koena bacteria o ka ʻōpū, hoʻohana pinepine ʻia ka lāʻau antibiotic ākea, hiki ke ulu nui ʻo C. difficile a hoʻopuka i nā toxins, e alakaʻi ana i ka maʻi.

Aia kēia hua bacteria ma nā mea ʻeluamea ʻonaa me nā ʻano non-toxigenic, akā ʻo nā maʻi toxigenic wale nō (toxins A a me B) ke kumu o ka maʻi. Hoʻoulu lākou i ka mumū ma o ka hoʻopau ʻana i nā cell epithelial intestinal. ʻO ka Toxin A he enterotoxin ka mea e hōʻino ai i ka ʻōpū o ka ʻōpū, hoʻonui i ka permeability, a me ka huki ʻana i nā cell immune e hoʻokuʻu i nā cytokine inflammatory. ʻO ka Toxin B, he cytotoxin ikaika loa, e kuhikuhi ana i ka cytoskeleton actin o nā pūnaewele, e alakaʻi ana i ka hoʻopuni ʻana o ke kelepona, ka wehe ʻana, a me ka make ʻana o ke kelepona. Hoʻohui pū ʻia kēia mau mea ʻawaʻawa i ka pōʻino o ka ʻiʻo a me ka pane kūlohelohe ikaika, e hōʻike ʻia e like me colitis, diarrhea, a ma nā hihia koʻikoʻi, pseudomembranous colitis-he ʻeha nui o ke kolonā.

PeheaC. Okoalaha?

Hoʻolaha maʻalahi ʻo C.Diff. Aia ia i loko o nā halemai, ʻike pinepine ʻia i loko o nā ICU, ma nā lima o nā limahana o ka haukapila, ma nā papahele a me nā lima lima, ma nā thermometer uila, a me nā mea lapaʻau ʻē aʻe ...

ʻO nā kumu pilikia no ka maʻi C. Diff

• ●ʻO ka hale maʻi lōʻihi;

• ●Ka lāʻau antimicrobial;

• ●Nā mea hana kemotherapy;

• ●ʻO ke kaʻina hana hou (nā lima ʻōpū, ka ʻoki ʻana i ka ʻōpū, ka ʻoki ʻana i ke koko);

• ●Naso-gastric meaʻai;

• ●ʻO ka maʻi C. diff mua;

Nā hōʻailona o ka maʻi C. Diff

Hiki ke ʻoluʻolu loa ka maʻi C. diff. ʻO ka hapa nui o ka poʻe e hoʻomau nei i ka maʻi maʻi a me ka ʻeha i ka ʻōpū. ʻO nā hōʻailona maʻamau: ʻo ka maʻi ʻeha, ka ʻeha o ka ʻōpū, ka nausea, pau ka ʻai, ke kuni.

I ka lilo ʻana o ka maʻi C. diff i ʻoi aku ka koʻikoʻi, e ulu ana kahi ʻano paʻakikī o C. diff i kapa ʻia ʻo colitis, pseudomembranous enteritis a me ka make.

ʻIkepilio C. Diff Infection

Moʻomeheu Bacterial:ʻAʻole hiki ke hoʻokaʻawale i nā maʻi toxigenic a me ka non-toxigenic;

Moʻomeheu Toxin:hōʻike i nā ʻano ʻawaʻawa e hoʻoulu ai i ka maʻi akā hoʻopau manawa (3-5 mau lā) a emi ʻole ka maʻi;

ʻIke GDH:wikiwiki (1-2hrs) a me ke kumu kūʻai, paʻakikī loa akā ʻaʻole hiki ke hoʻokaʻawale i nā koʻikoʻi toxigenic a me ka non-toxigenic;

ʻO ka hoʻāʻo ʻana o ka hoʻomaʻamaʻa hoʻoneʻe ʻana o ka Cell Cytotoxicity (CCNA):ʻike i ka toxin A a me B me ka naʻau kiʻekiʻe akā e hoʻopau ana i ka manawa (2-3 mau lā), a koi i nā lako kūikawā a me nā limahana i aʻo ʻia;

Toxin A/B ELISA: Ho'āʻo maʻalahi a wikiwiki (1-2hrs) me ka haʻahaʻa haʻahaʻa a me nā hewa hewa pinepine;

Nā ho'āʻo hoʻonui ʻana i ka ʻakika nucleic (NAATs): Ka wikiwiki (1-3hrs) a me ke ko'iko'i a me ke kiko'ī, e 'ike ana i nā genes kuleana no ka hana 'ino;

Eia hou, hiki ke hoʻohana ʻia nā hoʻāʻo kiʻi no ka nānā ʻana i nā ʻōpū, e like me ka CT scans a me nā hihi X, e kōkua i ka ʻike ʻana o C. diff a me nā pilikia o C. diff, e like me ka colitis.

Lapaʻau ʻana i ka maʻi C. Diff

Nui nā koho lapaʻau i loaʻa noC. ma'i 'oko'a. Aia ma lalo nā koho maikaʻi loa:

• ●Hoʻohana mau ʻia nā lāʻau lapaʻau waha e like me vancomycin, metronidazole a i ʻole fidaxomicin no ka mea hiki i ka lāʻau lapaʻau ke hele i loko o ka ʻōnaehana digestive a hiki i ke kolonā kahi e noho ai ka bacteria C. diff.

• ●Hiki ke hoʻohana ʻia ka metronidazole intravenous no ka mālama ʻana inā he koʻikoʻi ka maʻi C. diff.

• ●Ua hōʻike ʻia ka maikaʻi o ka hoʻololi ʻana i ka microbiota fecal i ka mālama ʻana i nā maʻi C. diff mau a me nā maʻi C. diff koʻikoʻi i pane ʻole i nā lāʻau ʻokoʻa.

• ●Pono paha ka ʻoki ʻana no nā maʻi koʻikoʻi.

ʻO ka hoʻonā diagnostic mai MMT

I ka pane ʻana i ka pono o ka ʻike wikiwiki a pololei o C. difficile, hoʻolauna mākou i kā mākou Nucleic Acid Detection Kit no ka Clostridium difficile toxin A/B gene, e hoʻoikaika ana i nā limahana mālama ola e hana i ka hōʻoia mua a pololei a kākoʻo i ka hakakā ʻana i nā maʻi i loaʻa i ka haukapila.

图片链接：

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  ●Kiekie Kiekie: ʻIke i ka haʻahaʻa200 CFU/mL,;

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  ●Hoʻoholo pololei: Hoʻomaopopo pololei i ka C. difficile toxin A/B gene, e hōʻemi ana i nā hopena hoʻopunipuni;

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  ●ʻIke ʻana i nā maʻi maʻi: Hoʻohana i ka hoʻāʻo nucleic acid e ʻike pololei i nā genes toxin, e hoʻokumu i kahi kūlana gula no ka diagnostics.

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  ●Pili piha menā mea hana PCR nui e kamaʻilio ana i nā labs hou aʻe;

Laʻana-i-PaneHoʻonā ma ka Macro & Micro-Test's AIO800 Mobile PCR Lab

 

• ●Laʻana-i-Pane Automation - E hoʻouka pololei i nā paipu hāpana kumu (1.5–12 mL), e hoʻopau i ka paipu lima. ʻO ka unuhi ʻana, ka hoʻonui ʻana, a me ka ʻike ʻana ua hoʻopiha piha ʻia, e hōʻemi ana i ka manawa lima a me ka hewa kanaka.

• ●ʻEwalu-Layer Contamination Protection - ʻO ke kahe ʻana o ke ea, ke kaomi maikaʻi ʻole, ka kānana HEPA, ka sterilization o UV, nā hopena i hoʻopaʻa ʻia, a me nā mea palekana i hoʻohui ʻia e pale i nā limahana a hōʻoia i nā hopena hilinaʻi i ka wā o ka hoʻāʻo kiʻekiʻe.

No nā kikoʻī hou aku:

https://www.mmtest.com/nucleic-acid-detection-kit-for-clostridium-difficile-toxin-ab-gene-fluorescence-pcr-product/

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