Ua lilo ʻo Antimicrobial resistance (AMR) i kekahi o nā mea hoʻoweliweli olakino nui loa o kēia kenekulia, e hoʻopiʻi pololei ana ma luna o 1.27 miliona mau make i kēlā me kēia makahiki a hāʻawi ʻia i kahi kokoke i 5 miliona mau mea make-ke koi nei kēia pilikia olakino olakino i kā mākou hana koke.
ʻO kēia World AMR Awareness Week (Nowemapa 18-24), hui pū nā alakaʻi olakino honua i kā lākou kāhea:"E hana i kēia manawa: pale i kā mākou manawa, palekana i ko mākou wā e hiki mai ana."Hōʻike kēia kumumanaʻo i ka wikiwiki o ka kamaʻilio ʻana i ka AMR, e koi ana i nā hana i hoʻonohonoho ʻia ma waena o ke olakino kanaka, olakino holoholona, a me nā ʻāpana kaiapuni.
ʻO ka hoʻoweliweli o AMR ma mua o nā palena aupuni a me nā kāʻei mālama olakino. Wahi a ka noiʻi Lancet hou loa, me ka ʻole o nā hana kūpono e kūʻē iā AMR,hiki i ka 39 miliona mau make ma ka honua holoʻokoʻa ma 2050, ʻoiai ke manaʻo nei e piʻi aʻe ke kumukūʻai makahiki no ka mālama ʻana i nā maʻi kūʻē i ka lāʻau mai ka $66 biliona a hiki i kēia manawa.$159 biliona.
Pilikia AMR: ʻO ka ʻoiaʻiʻo koʻikoʻi ma hope o nā helu
Hiki ke kū'ē i ka antimicrobial (AMR) ke pane hou nā microorganisms—bacteria, viruses, parasites, and fungi—i nā lāʻau antimicrobial maʻamau. Ua hōʻea kēia pilikia olakino honua i nā ʻāpana weliweli:
-I kēlā me kēia 5 minuke, make 1 kanaka mai ka ma'i kū'ē i ka antibiotic
-Na2050, hiki i ka AMR ke hōʻemi i ka GDP honua ma 3.8%
-96% o nā ʻāina(186 huina) i komo i ka 2024 global AMR tracking survey, e hōʻike ana i ka ʻike ākea o kēia hoʻoweliweli.
-Ma nā keʻena mālama koʻikoʻi ma kekahi mau wahi,ʻoi aku ma mua o 50% o nā mea hoʻokaʻawale bacteriahōʻike kūʻē i hoʻokahi lāʻau antibiotic
Pehea e hāʻule ai nā lāʻau antibiotic: nā ʻano hana pale o nā microorganism
Hana nā lāʻau antibiotic ma ka huli ʻana i nā kaʻina hana bacteria koʻikoʻi:
-Hoʻohui ʻia o ka pā kelepona: Hoʻopilikia nā penicillins i nā paia o nā pūnaewele bacteria, ka mea e haki ai ka maʻi bacteria a make
-Hana ʻia ka Protein: Hoʻopaʻa nā Tetracyclines a me nā macrolides i nā ribosome bacteria, hoʻopau i ka synthesis protein
-DNA/RNA Replication: Kāohi nā Fluoroquinolones i nā enzyme i koi ʻia no ka hana hou ʻana o ka DNA bacteria
-Paʻa Paʻa Pūnaewele: Hoʻopilikia nā Polymyxins i nā membrane cell bacteria, e alakaʻi ana i ka make cell
-Alanui Metabolic: Pale nā Sulfonamides i nā kaʻina hana bacteria koʻikoʻi e like me ka synthesis o ka waikawa folic
Eia nō naʻe, ma o ke koho kūlohelohe a me nā hoʻololi genetic, hoʻomohala ka bacteria i nā hana he nui e kūʻē i nā lāʻau antibiotic, me ka hana ʻana i nā enzyme inactivating, hoʻololi i nā pahuhopu lāʻau, hōʻemi i ka hōʻiliʻili lāʻau, a me ka hana ʻana i nā biofilms.
Carbapenemase: ʻO ka "Super Weapon" i ka pilikia AMR
Ma waena o nā ʻano hana kū'ē like ʻole, ka hana ʻana onā carbapenemasespili loa. Hoʻopau kēia mau enzymes i nā lāʻau lapaʻau carbapenem-i manaʻo pinepine ʻia i nā lāʻau lapaʻau "laina hope". Hana ʻo Carbapenemases ma ke ʻano he "mea kaua nui," e wāwahi ana i nā lāʻau antibiotic ma mua o ke komo ʻana i nā cell bacteria. ʻO nā huakini e lawe ana i kēia mau enzymes—e like meKlebsiella pneumoniaeaAcinetobacter baumannii- hiki ke ola a hoʻonui i ka wā i ʻike ʻia i nā lāʻau ʻokoʻa ikaika loa.
ʻO ka mea weliweli loa, aia nā genes encoding carbapenemases ma nā ʻano genetic mobile hiki ke hoʻololi i waena o nā ʻano bacteria like ʻole,e hoʻolalelale ana i ka hoʻolaha ʻana o ka maʻi bacteria multidrug-resistant.
Hoʻomaʻamaʻas: ʻO ka laina mua o ka pale ma ka AMR Control
He mea koʻikoʻi ka diagnostics pololei a me ka wikiwiki i ka hakakā ʻana i ka AMR. ʻO ka ʻike ʻana i ka manawa kūpono o nā bacteria kū'ē hiki ke:
-E alakaʻi i ka mālama pono ʻana, e pale aku i ka hoʻohana ʻana i ka antibiotic pono ʻole
-E hoʻokō i nā hana hoʻomalu i ka maʻi e pale ai i ka hoʻoili ʻia ʻana o nā bacteria kū'ē
-Mālama i nā ʻano kūʻē e hoʻomaopopo i nā hoʻoholo olakino olakino
ʻO kā mākou mea hoʻonā: Nā mea hana hou no ka hakakā AMR pololei
No ka hoʻoponopono ʻana i ka luʻu AMR e ulu nei, ua hoʻomohala ʻo Macro & Micro-Test i ʻekolu mau pahu ʻike carbapenemase hou e hālāwai ana i nā pono lapaʻau like ʻole, e kōkua ana i nā mea mālama olakino e ʻike wikiwiki a pololei i ka maʻi bacteria e hōʻoia i nā hana kūpono a me ka hoʻomaikaʻi ʻana i nā hopena maʻi.
1. ʻO Carbapenemase Detection Kit (Colloidal Gold)
Hoʻohana i ka ʻenehana gula colloidal no ka ʻike wikiwiki ʻana i ka carbapenemase. He kūpono no nā halemai, nā halemai, a me ka hoʻohana ʻana i ka home, e hoʻomaʻamaʻa i ke kaʻina diagnostic me ka pololei kiʻekiʻe.
ʻO nā pono kumu:
-ʻIke piha: Hoʻomaopopo like i nā genes kū'ē ʻelima—NDM, KPC, OXA-48, IMP, a me VIM
-Nā hopena wikiwiki: Hāʻawi i nā hopena i loko15 minuke, ʻoi aku ka wikiwiki ma mua o nā hana kuʻuna (1-2 lā)
-Hana maʻalahi: ʻAʻohe mea paʻakikī a hoʻomaʻamaʻa kūikawā paha e pono ai, kūpono no nā ʻano hoʻonohonoho like ʻole
-Kiekie Pono: 95% ka naʻau me ka hoʻopunipuni ʻole mai nā maʻi bacteria maʻamau e like me Klebsiella pneumoniae a i ʻole Pseudomonas aeruginosa
2. Carbapenem Resistance Gene Detection Kit (Fluorescence PCR)
Hoʻolālā ʻia no ka loiloi genetic hohonu o ka pale ʻana i ka carbapenem. Kūpono no ka mākaʻikaʻi piha ʻana i nā keʻena hoʻokolohua lapaʻau, e hāʻawi ana i ka ʻike kikoʻī o nā genes kūʻē carbapenem.
ʻO nā pono kumu:
-Hoʻolāʻau maʻalahi: ʻIke pololei mainā kolo maʻemaʻe, ka sputum, a i ʻole nā ʻauʻau ʻāʻī - ʻaʻohe moʻomeheupono
-Hoemi Kumukuai: E ʻike i nā ʻano genes kūʻē nui ʻeono (NDM, KPC, OXA-48, OXA-23) IMP, a me VIM i hoʻokahi hoʻokolohua, e hoʻopau ana i ka hoʻāʻo hou ʻana.
-Kiʻekiʻe ʻike a me ka kikoʻī: ʻO ka palena ʻike ma lalo o 1000 CFU/mL, ʻaʻohe hoʻololi keʻa me nā genes kū'ē ʻē aʻe e like me CTX, mecA, SME, SHV, a me TEM
-Kūlike ākea: Pili meLaʻana-i-PaneAIO 800 molecular POCT a me nā mea hana PCR mainstream
3. Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa a me Resistance Genes Multiplex Detection Kit (Fluorescence PCR)
Hoʻohui kēia kit i ka ʻike bacteria a me nā mīkini kūʻē e pili ana i loko o kahi kaʻina streamline hoʻokahi no ka ʻike kūpono.
ʻO nā pono kumu:
-ʻIke piha: Hōʻike i ka manawa likeʻekolu mau mea maʻi bacterial nui—Klebsiella pneumoniae, Acinetobacter baumannii, a me Pseudomonas aeruginosa—a ʻike i ʻehā mau genes carbapenemase koʻikoʻi (KPC, NDM, OXA48, a me IMP) i hoʻokahi hoʻokolohua.
-Kiekie Kiekie: Hiki ke ʻike i ka DNA bacteria ma ka haʻahaʻa e like me 1000 CFU/mL
-Kākoʻo i ka hoʻoholo hoʻoholo lāʻau lapaʻau: Hoʻomaʻamaʻa i ke koho ʻana i nā lāʻau antimicrobial maikaʻi ma o ka ʻike mua ʻana i nā maʻi kūʻē
-Kūlike ākea: Pili meLaʻana-i-PaneAIO 800 molecular POCT a me nā mea hana PCR mainstream
Hāʻawi kēia mau pahu ʻike i nā limahana mālama olakino me nā mea hana e hoʻoponopono ai i ka AMR ma nā pae like ʻole-mai ka hoʻāʻo wikiwiki ʻana i ka hoʻāʻo ʻana i nā genetic kikoʻī kikoʻī—e hōʻoia ana i ka hoʻopaʻa ʻana i ka manawa a me ka hōʻemi ʻana i ka hoʻolaha ʻana o ka bacteria kū'ē.
Ke kaua ʻana i ka AMR me ka Precision Diagnostics
Ma Macro & Micro-Test, hāʻawi mākou i nā pahu diagnostic ʻokiʻoki e hoʻoikaika i nā mea mālama olakino me nā ʻike wikiwiki, hilinaʻi, hiki i ka hoʻoponopono ʻana i ka manawa kūpono a me ka hoʻopaʻa ʻana i ka maʻi maʻi.
E like me ka mea i koʻikoʻi ʻia i ka World AMR Awareness Week, ʻo kā mākou koho i kēia lā e hoʻoholo i ko mākou hiki ke pale aku i nā hanauna o kēia manawa a me ka wā e hiki mai ana mai ka hoʻoweliweli ʻana o ka pale antimicrobial.
E hui pū me ke kūʻē ʻana i ka antimicrobial - ʻo kēlā me kēia ola i mālama ʻia.
For more information, please contact: marketing@mmtest.com
Ka manawa hoʻouna: Nov-19-2025