Ua hōʻike ʻia kahi noiʻi metagenomic hou i kahi ʻano like ʻole o nā virus a me nā bacteria i lawe ʻia e nā rodents ma ka Panalāʻau ʻo Heilongjiang, me ka virus Lassa, ka virus Amur, Salmonella, a me Yersinia pestis.
Ua hoʻohana ka noiʻi i kaPatch Enrichment Kit Pathogen RNA mai Macro & Micro-Test, ma muli o ka ʻenehana hopu probe. Ma ka hoʻopau koho ʻana i ka host rRNA a me nā ʻāpana host ʻē aʻe i mālama ʻia, ua mālama pono ke ʻano i ka microbial RNA, e hoʻomaikaʻi nui ana i ka ʻike ʻana o ka pathogen. He mea koʻikoʻi kēia hana hoʻonui RNA pathogen i ka hoʻokō ʻana i kahi helu ʻike kiʻekiʻe a hāʻawi i ke kākoʻo loea ikaika no ka nānā ʻana i nā pathogen.
Nā ʻIole: Nā Waihona Koʻikoʻi o nā Maʻi Zoonotic
ʻO nā ʻiole ka hui mammals waiwai nui loa i nā ʻano holoholona a laha nui hoʻi, nona ma mua o 2,000 mau ʻano mammals ma ka honua holoʻokoʻa a ʻoi aku ma mua o 40% o nā ʻano mammals āpau.
Ma waho aʻe o ko lākou koʻikoʻi kaiaola, lawelawe nā rodents i mau waihona nui a me nā mea lawe o nā maʻi pathogens zoonotic he nui.Ma muli o ka launa pinepine ʻana o nā wahi noho o nā ʻiole me nā wahi noho kanaka—ma o nā nahu pololei, ka pili ʻana me nā ʻōpala, a i ʻole ka laha pololei ʻole ʻana ma o nā ʻuku a me nā mites—ʻo nā maʻi pathogens a lākou e mālama nei he mau hoʻoweliweli mau i ke olakino lehulehu.
ʻO ka mea nui, ʻoi aku ma mua o 70% o nā maʻi lele e kū mai ana mai nā holoholona hihiu, me nā rodents e hōʻike ana i kekahi o nā waihona viral koʻikoʻi loa.
ʻĀpana Palena ʻo Heilongjiang: He Laina Mua no ka Nānā ʻana i nā Mathogen
ʻO Heilongjiang, he panalāʻau palena ma ka ʻākau hikina o Kina, he nui nā kumuwaiwai kaiaolaola a kaʻana like i nā palena me nā ʻāina he nui. ʻO ka hui pū ʻana o ka biodiversity waiwai a me ka neʻe pinepine ʻana o ka heluna kanaka ma waena o nā palena e hana i nā kūlana kūpono no ka hoʻolaha ʻana o nā pathogens.
Ma waena o Iune a me Iulai 2021, ua hōʻiliʻili nā kānaka noiʻi i 67 mau ʻiole hihiu mai ke kūlanakauhale ʻo Hengdaohezi, ke kūlanakauhale ʻo Mudanjiang. ʻO nā laʻana:
l 20ʻApodemus peninsulae
l 47ʻO Myodes rufocanus
Ua hopu ʻia nā hāpana a pau ma nā wahi noho a me nā ʻāina mahiʻai e pili ana, e hōʻike ana i ka pilina kokoke ma waena o nā wahi noho kanaka a me nā wahi noho holoholona hihiu.
ʻEnehana Hoʻonui Pathogen: Ke Lanakila nei i ka Hoʻopilikia ʻana o ka Pūnaewele Hoʻokipa
I ke kaʻina hana metagenomic, ʻo ka RNA kikowaena ka mea maʻamau e hoʻomalu i nā heluhelu kaʻina hana, e uhi ana i nā hōʻailona pathogen haʻahaʻa.
No ka hoʻoponopono ʻana i kēia pilikia, ua hoʻohana ka noiʻi iʻO ka Patch Metagenomic Detection Kit a Macro & Micro-Test. Ma ka hoʻohana ʻana i ka ʻenehana hopu probe, ua hoʻopaʻa nā probes i hoʻolālā kūikawā ʻia i ka rRNA host a me nā kaʻina i mālama ʻia, e hiki ai ke hoʻopau ʻia a no laila e hoʻonui ai i ka RNA microbial.
Ua hoʻomaikaʻi nui kēia ʻano hana i ka ʻike ʻana i nā pathogen, e ʻae ana i ka hoʻonohonoho ʻana ma hope e hoʻihoʻi i kahi hapa nui o nā heluhelu pathogen. Ua hoʻokumu ke kaʻina hoʻonui i kahi kahua paʻa no ka wehewehe pono ʻana i ka spectrum pathogen i lawe ʻia e nā rodents.
Ma hope o ka hoʻonui ʻana, ua hana ʻia nā laʻana RNA i ka hoʻololi ʻana i ke kākau ʻana, ke kūkulu ʻana i ka waihona puke, a me ke kaʻina hana kiʻekiʻe. Ua komo pū ka loiloi Bioinformatic:
Kānana genome kikowaena l
Hoʻokaʻawale taxonomic me ka hoʻohana ʻana iā Kraken2
Hoʻoponopono nui me Bracken
Ua hoʻokumu kēia kaʻina hana i kahi ʻikepili piha o nā kaiāulu viral a me nā bacteria.
Nā ʻIke Noiʻi: Ka Hoʻolaha Pū ʻana o nā Virus a me nā Bacteria he Nui
Nā ʻIke Viral
No 21 mau ʻohana viral nā virus i ʻike ʻia, meʻArenaviridaea meʻO Hantaviridae.
Ma onovome ka hoʻohana ʻana iā Megahit, ua hana ʻia he 154 mau contigs viral, kahi i hoʻohālikelike ʻia me 110 mau virus mai nā ʻohana ʻewalu.
In ʻApodemus peninsulae, ua ʻike ʻia nā virus aʻe:
l Arenaviruses: Lassa virus, Wenzhou virus, Gairo virus
l Hantaviruses: Amur virus, Puumala virus
In ʻO Myodes rufocanus, ua ʻike ʻia ka maʻi arterivirus ʻiole a me ka maʻi Amur.
Ma waena o kēia mau pathogens:
ʻO ka maʻi Lassa kekahi kumu o ka maʻi hemorrhagic viral, me nā helu make hihia e hiki aku ana ma kahi o 20%.
ʻO ka maʻi Amur kekahi o nā pathogens i kuleana no ka maʻi hemorrhagic me ka renal syndrome (HFRS). Ua hōʻike ʻo Kina i ke kaumaha kiʻekiʻe loa o ka honua o nā maʻi hantavirus.
Nā ʻIke Bacteria
Ua hōʻike ʻia he 1,051 mau ʻano bacteria.
ʻO nā genera i nui loa:
lSalmonella(26–31%)
lʻO Yersinia(11–23%)
Salmonellahe pathogen nui i lawe ʻia e ka meaʻai, kuleana no kahi 9 miliona mau hihia o ka maʻi typhoid a me kahi 110,000 mau make i kēlā me kēia makahiki ma ka honua holoʻokoʻa.
ʻO Yersinia pestis, ke kumu o ka maʻi ahulau, ua kuleana no ʻekolu mau maʻi ahulau mōʻaukala. Ua ʻike ʻia ʻo Heilongjiang Province ʻo ia kekahi o nā wahi kūlohelohe o Kina no ka maʻi ahulau a ke noho nei ʻo ia he wahi koʻikoʻi no ka nānā ʻana i nā maʻi ahulau.
Ke Koʻikoʻi o ke Aʻo ʻana
Nā Hāʻawi ʻEpekema
ʻO kēia haʻawina ka hōʻike mua o nā ʻāpana maʻi Lassa a me ka maʻi arteritis iole i loko o nā rodents mai Heilongjiang, e hoʻonui ana i ka waihona ʻikepili pathogen i lawe ʻia e nā rodent ma Kina.
Hoʻākāka pono ia i nā kaiāulu viral a me nā bacteria i nā heluna rodent kūloko, e hāʻawi ana i ka ʻikepili kumu no ka nānā ʻana i nā maʻi zoonotic ma nā wahi palena.
Nā hopena o ke olakino lehulehu
Hōʻike nā ʻike i ka pono no ka nānā mau ʻana a me ka nānā ʻana i nā pathogensA. peninsulaea meM. rufocanus.
Hāʻawi ka ʻikepili i nā hōʻike ʻepekema e kākoʻo ana i nā hoʻolālā kaohi kumu no nā maʻi e like me ke ahulau a me ke kuni hemorrhagic me ka renal syndrome.
Nā Ikaika Hana
ʻO ka hoʻonohonoho ʻana o Metagenomic e hiki ai ke ʻike kūʻokoʻa i nā pathogens i ʻike ʻia a me nā pathogens hou.
Ma kēia haʻawina, ua hōʻike ka ʻenehana hoʻonui pathogen a Macro & Micro-Test i ka hana ikaika, e hoʻomaikaʻi pono ana i ka ʻike ʻana i ka pathogen i nā hāpana olaola paʻakikī. Hōʻoia nā hopena i kona hiki ke kākoʻo i ka ʻike ʻana i ka pathogen kiʻekiʻe i ka nānā ʻana i nā holoholona hihiu.
Manaʻo Huahana
Ma muli o kāna hoʻohana pono ʻana i kēia haʻawina, ua ʻōlelo nui ʻia ka Macro & Micro-Test Pathogen RNA Enrichment Kit no ka noiʻi kiaʻi metagenomic.
Ma ka hoʻopau pono ʻana i nā waikawa nucleic host a me ka hoʻonui ʻana i nā moʻo microbial, hoʻomaikaʻi nui ka pahu i ka ʻike ʻana a me ka maikaʻi o ka ʻikepili. Hōʻike ia i kahi mea hana koʻikoʻi no ka ʻike pololei ʻana i nā pathogen i nā laʻana paʻakikī a hāʻawi i ke kākoʻo loea ikaika no ka nānā ʻana i ke olakino lehulehu, ka loiloi pilikia zoonotic, a me ka mākaukau no ka maʻi ahulau.
Contact to learn more: marketing@mmtest.com
Ka manawa hoʻouna: Malaki-02-2026