ʻO ka Mycobacterium Tuberculosis Rifampicin Resistance
Inoa mea kūʻai
HWTS-RT074A-Mycobacterium Tuberculosis Rifampicin Resistance Detection Kit (Fluorescence PCR)
Epidemiology
Ua hoʻohana nui ʻia ka Rifampicin i ka mālama ʻana i nā maʻi maʻi maʻi maʻi mai ka hopena o 1970s, a he hopena koʻikoʻi.ʻO ia ke koho mua e hoʻopōkole i ka chemotherapy o nā maʻi maʻi maʻi maʻi pulmonary.ʻO ke kūʻē ʻana o Rifampicin ma muli o ka hoʻololi ʻana o ka gene rpoB.ʻOiai ke puka mau nei nā lāʻau anti-tuberculosis hou, a ke hoʻomau nei ka maikaʻi o ka lāʻau lapaʻau o ka poʻe maʻi maʻi maʻi pulmonary tuberculosis, aia nō ka nele o nā lāʻau anti-tuberculosis, a ʻoi aku ka kiʻekiʻe o ke ʻano o ka hoʻohana ʻana i ka lāʻau lapaʻau i ka lāʻau lapaʻau.Akaka, ka Mycobacterium tuberculosis i loko o nā mea maʻi me ka pulmonary tuberculosis hiki ole loa pepehi i ka manawa kūpono, ka mea hope alakai i ka likeʻole degere o ka lāʻau kū'ē i loko o ke kino o ka mea maʻi, hooloihi aku i ka papa o ka maʻi, a hoʻonui i ka pilikia o ka make o ka mea maʻi.He kūpono kēia pahu no ka hōʻoia kōkua o ka Mycobacterium tuberculosis maʻi a me ka ʻike ʻana i ka rifampicin resistance gene, he mea kōkua e hoʻomaopopo i ke kūʻē ʻana i ka lāʻau o ka mycobacterium tuberculosis i hoʻopili ʻia e nā maʻi, a me ka hāʻawi ʻana i nā mea kōkua no ke alakaʻi ʻana i ka lāʻau lapaʻau.
Epidemiology
Inoa Pahuhi | Mea hoolaha | Quencher | ||
Paʻa PaʻaA | Paʻa PaʻaB | Paʻa PaʻaC | ||
rpoB 507-514 | rpoB 513-520 | IS6110 | FAM | ʻAʻohe |
rpoB 520-527 | rpoB 527-533 | / | CY5 | ʻAʻohe |
/ | / | Ka hooponopono kuloko | HEX(VIC) | ʻAʻohe |
Nā ʻāpana ʻenehana
Waihona | ≤-18 ℃ I ka pōʻeleʻele |
Kau-ola | 9 mahina |
ʻAno Hoʻohālike | Sputum |
CV | <5% |
LoD | ʻano ʻāhiu kūʻē rifampicin: 2x103bacteria/mL homozygous mutant: 2x103bacteria/mL |
kikoo | ʻIke ʻo ia i ka mycobacterium tuberculosis ʻano ʻāhiu a me nā pae hoʻololi o nā genes kū'ē lāʻau ʻē aʻe e like me katG 315G>C\A, InhA-15C>T, hōʻike nā hopena hōʻike ʻaʻole kūʻē i ka rifampicin, ʻo ia hoʻi, ʻaʻohe cross-reactivity. |
Nā mea hana pili: | SLAN-96P Pūnaehana PCR manawa maoli(Hongshi Medical Technology Co., Ltd. ) |