Ua paʻi ʻia kahi noiʻi koʻikoʻi i kēia manawa maʻO ka Lancetua hōʻike i kahi ʻoiaʻiʻo kaumaha:1.27 miliona mau make i ka makahiki 2019ua pili pono ʻia ike kū'ē ʻana i nā antimicrobial (AMR)ʻOi aku ka hopohopo,Ua hana ʻia he 73% o kēia mau make e nā pathogens ʻeono wale nō:
1.ʻO ka maʻi Escherichia coli
2.ʻO Staphylococcus aureus
3.ʻO ka maʻi pneumoniae Klebsiella
4.ʻO ka maʻi niumonia Streptococcus
5.ʻO Acinetobacter baumannii
6.ʻO Pseudomonas aeruginosa
I waena o lākou,ʻO ka maʻi pneumoniae Klebsiella (KPN), ʻO Acinetobacter baumannii (Aba), a meʻO Pseudomonas aeruginosa (PA)kū i waho ma ke ʻano he mea kōkua nui i nā maʻi i loaʻa i ka haukapila a me ke kūʻē ʻana i nā lāʻau he nui. Ke kūpaʻa nei kēia mau pathogens inā carbapenems—ko mākou laina pale hope loa—he mea hoʻoweliweli nui ia no ke olakino honua.
Ke hoʻomaopopo nei iā KPN, Aba, a me PA
-ʻO ka maʻi pneumoniae Klebsiella (KPN)
He pathogen kūpono ʻo KPN a he kumu nui ohaukapila i loaʻanā maʻi ʻehaKe hoʻopilikia ʻia ka pale ʻana o ka mea hoʻokipa, hiki iā ia ke komo ma o ke ala hanu, e hana ana i ka maʻi pneumonia, nā maʻi koko, a me ka sepsis. ʻO ka mea hopohopo nui kaʻano hvKp ST23 hypervirulent, kahi e lawe pinepine ai i nā genes carbapenemase e like meKPC, NDM, OXA-48, a me IMP, e hoʻolilo ana i ka mālama ʻana i mea paʻakikī loa.
-ʻO Acinetobacter baumannii (Aba)
He pathogen haukapila kūpaʻa loa ʻo Aba i hiki ke ola ma luna o nā ʻili no nā wā lōʻihi. He kumu nui ia oka niumonia e pili ana i ka ventilator (VAP)a me nā maʻi pili i ka ICU. ʻO kona hiki ke loaʻa i nā genes pale ua hoʻolilo ia i hoʻokahi o nā mea weliweli loanā meaola kū'ē i nā lāʻau lapaʻau like ʻole (MDR), me ke kūpaʻa ʻana o ka carbapenem e ʻoi aku ana50% ma kekahi mau ʻāpana.
-ʻO Pseudomonas aeruginosa (PA)
He bacteria Gram-negative ʻo PA i hana ʻole ʻia nona ke kuleana nonā maʻi ʻōpū hanu haʻahaʻa, ʻoi aku hoʻi i nā poʻe maʻi immunocompromised. ʻO kona hiki ke hoʻololi, ka wikiwiki o ka mutation, a meka hiki ke hana i ka biofilme paʻakikī ai ke hoʻopau ʻana i nā maʻi.PA (CRPA) pale-Carbapenemhe pilikia lapaʻau honua mau loa ia.
Pehea e laha ai kēia mau pathogens
Hoʻolaha nui ʻia nā pathogens MDR ma o:
-Nā wahi hoʻokipa:nā lako i haumia, nā ʻili, a me nā lima o nā limahana olakino
-Hoʻokaʻaʻike pololei:nā mea maʻi i loaʻa i ka maʻi a i ʻole nā mea lawe asymptomatic
-Nā kulu hanu:ʻoi aku hoʻi no nā ʻano maʻi e pili ana i ka pneumonia
-Nā kaʻina hana komo:nā mīkini hanu, nā catheters, a me nā mea hana ʻoki kino
Nā Pilikia i ka Lāʻau Lapaʻau
-Ke kū'ē ʻana iā Carbapenem
Ua manaʻo ʻia nā Carbapenemsnā lāʻau antibiotic hope loaʻO ka puka ʻana mai o nā bacteria e hana ana i ka carbapenemase ua kaupalena nui i ko lākou pono.
-Nā Koho Lapaʻau Palena
-Polymyxins (e laʻa, colistin): kūpono akā ʻawahia loa
-Tigecycline: nā hōʻailona palena
-Nā mea hana hou (cefiderocol, sulbactam-durlobactam): loaʻa kūpono akā palena ʻia
ʻOi aku ka koʻikoʻi o ka pale ʻana a me ka ʻike mua ʻana i kēia manawa ma mua o ka wā ma mua.
Ka Pono no ka ʻIke Wikiwiki a Pololei
ʻO kēia mau pathogens ke kumu o kahi hapa nui o nā make e pili ana i ka AMR ma ka honua holoʻokoʻa, e hōʻike ana i ka pono wikiwiki nonā hōʻoia wikiwiki a hilinaʻi hoʻie alakaʻi i ka lāʻau lapaʻau kūpono.
Hoʻopakele ka ʻike mua ʻana i nā ola
No ka hoʻoponopono ʻana i kēia pono lapaʻau wikiwiki,ʻO ka Macro & Micro-Test's KPN, Aba, PA & Drug Resistance Genes Multiplex Detection Kithāʻawi i kahi hopena ikaika.
He hopena hou,Pahu ʻIke Multiplex a Macro & Micro-Test, hiki ke ʻike like ʻia oʻO KPN, Aba, PA, a me nā genes carbapenemase koʻikoʻi-KPC, NDM, ʻOXA-48, a meIMP.
Nā Pōmaikaʻi Koʻikoʻi:
- ʻIke pololei ʻia mai nā hāpana sputum, e hoʻopau ana i nā kaʻina hana moʻomeheu lōʻihi.
- Kiʻekiʻe ke kikoʻī a me ka ʻike(LoD: 1000 CFU/mL) no nā hopena pololei.
- Ka manawa hoʻololi wikiwiki—ʻo ka hopena he 35 wale nō-50mau minuke.
- Kūlike me nā ʻōnaehana PCR maʻamau, e hōʻoiaʻiʻo ana i ka hiki ke komo ākea.
He Kāhea i ka Hana: Ke Hoʻoikaika nei i ke Kaua Kūʻē i nā Superbugs
KiʻekiʻePahu ʻIke MultiplexseHoʻāʻo Macro & Micro hāʻawi i kahi pono koʻikoʻi i ka ʻike wikiwiki a me ka pololei ʻana i nā pathogens kūʻē, hiki ke nānā pono, nā diagnostics wikiwiki, a me nā hoʻolālā lapaʻau i kuhikuhi ʻia, kahi e hoʻomaikaʻi hope ai i nā hopena o ka mea maʻi a me ka kaohi ʻana i ka laha ʻana o ke kūʻē antibiotic.
Contact if interested: marketing@mmtest.com
Ka manawa hoʻouna: Ian-08-2026