ʻO ka waikawa nucleic Zaire a me Sudan Ebolavirus i hoʻomaloʻo ʻia

No Filoviridae ka Ebolavirus, he maʻi RNA kaula hoʻokahi ʻole i hoʻokaʻawale ʻia. He mau filaments lōʻihi nā maʻi me ka lōʻihi virion awelika o 1000nm a me ke anawaena o kahi o 100nm. ʻO ka genome Ebolavirus he RNA kaula ʻole i hoʻokaʻawale ʻia me ka nui o 18.9kb, e hoʻopili ana i 7 mau protein kūkulu a me 1 protein ʻaʻole kūkulu. Hiki ke hoʻokaʻawale ʻia ka Ebolavirus i nā ʻano e like me Zaire, Sudan, Bundibugyo, Tai Forest a me Reston. I waena o lākou, ua hōʻike ʻia ke ʻano Zaire a me ke ʻano Sudan e make ai nā kānaka he nui mai ka maʻi. ʻO ka EHF (Ebola Hemorrhagic Fever) kahi maʻi maʻi hemorrhagic acute i hoʻokumu ʻia e ka Ebolavirus. Hoʻopili nui ʻia nā kānaka ma o ka hoʻopili ʻana me nā wai o ke kino, nā mea huna a me nā ʻōpala o nā maʻi a i ʻole nā ​​​​holoholona i loaʻa i ka maʻi, a ʻo nā hōʻike lapaʻau e puka nui ana ke kuni, ke kahe ʻana o ke koko a me ka hōʻino ʻana o nā ʻōpū he nui. He kiʻekiʻe ka make ʻana o ka EHF he 50%-90%. I kēia manawa, ʻo nā ʻano hana o ka ʻike ʻana i ka maʻi Ebola he mau hoʻokolohua hoʻokolohua nui ia, me ʻelua mau ʻano: ka ʻike ʻana i ke kumu a me ka ʻike ʻana i ka serological. ʻO ka ʻike ʻana i ke kumu e pili ana i ka ʻike ʻana i nā antigens viral i loko o nā hāpana koko e ELISA, ka ʻike ʻana i nā waikawa nucleic ma o nā ʻano hoʻonui e like me RT-PCR, a pēlā aku, a me ka hoʻohana ʻana i nā cell Vero, Hela, a pēlā aku no ka hoʻokaʻawale ʻana a me ka moʻomeheu ʻana i ka maʻi. ʻO ka ʻike ʻana i ka serological e pili ana i ka ʻike ʻana i nā antibodies IgM kikoʻī Serum ma ka hopu ʻana iā ELISA, a me ka ʻike ʻana i nā antibodies IgG kikoʻī Serum e ELISA, immunofluorescence, a pēlā aku.