Kanaka bcr-abl fusion gene gunction

ʻO ka myelogenoususeukemiamia nui ʻOi aku ma mua o 95% o nā mea maʻi CML e lawe i ka chromosome chromosome (ph) ma ko lākou mau koko koko. ʻO ka pastominant stomhogenesis o CML i penei BCR) Genera ma ka lima lōʻihi o Chromosome 22 (22Q11); Ua hoʻohuiʻia ka hui prosion fusion e kēia gyrostine kinase (TK), a e hana ai i nā mea hana ma lalo o ka heluʻana i nā wahi ka hopena o cml. ʻO Bcr-Abl kekahi o nā hōʻike diagnostic koʻikoʻi o CML. ʻO ka hoʻololiʻana o ka loaʻaʻana o kāna pae transcript ke kuhikuhi no ka hōʻoiaʻana o ka corgnostic o ka lemukemia a hiki ke hoʻohanaʻia i ka hanaʻana o Leukemia ma hope o ka mālamaʻana.