Kanaka eml4-alk fusion gene gu susion
Hua waihona
Hwts-TM006-Alm Fusion Genit General Entrition Decom Decom Device Decom)
HAAKAANA
Tfda
Epideminey
Ua hoʻohanaʻia kēia kī eʻike i nāʻano he 12 mutation mauʻano o nā mea maʻi eml4-alk i nā mea maʻi maʻi counter cunge cance. ʻO nā hopena hōʻike no ka hōʻikeʻana i keʻano o ka hoʻokeleʻana aʻaʻole pono e hoʻohanaʻia e like me ke kumu hoʻokahi no ka mālama pilikino. Pono nā poʻe hoʻokele e hana i nā hoʻoponopono kūlike ma nā hopena hōʻike e pili ana i nā mea e like me keʻano o ka mea maʻi, nā'ōlelo hōʻike lāʻau lapaʻau, a me nā hōʻike hōʻike lāʻau lapaʻau. ʻO ka pōʻino o lung ka mea nui loa i ka honua, a me 80% ~ 85% o nā hihia he mea liʻiliʻi liʻiliʻi (nsclc). ʻO ka fusion o ka cusion o echinderm micututubule-e pili ana i ka folin-like 4 (eml4) a me ka alk) ma keʻano he herclc. miliona miliona mau helu helu. Ma kahi o 20 mau mea hana e loaʻa ai nā mea likeʻole, ma waena o ka 12 Fusion Mika 33% a me 29% o nā mea maʻi me nā maʻi eml4-alk fusion gen nusclc, kūpono loa. Ua hōʻikeʻiaʻo Alk Toohiboror e CIIHITINIBIB i nā lāʻau liʻiliʻi-molecle i hoʻolālāʻia no nā lāʻau lapaʻau i hoʻokumuʻia no ka alk gion gounations. I ka hoʻopauʻana i ka hana o ka Alk Tyrostine Kinase Kinase, e kāohi ana i kona mau wahi e hele nei, e hoʻokō ai i ka lāʻau lapaʻau no nā'ōpala. Ua hōʻikeʻia nā haʻawina Clinical i hōʻikeʻiaʻo CIIZITIIB i kahi helu o ka 61% ma nā mea maʻi eml4-alk Fusivalication No laila,ʻo kaʻikeʻana o ka mikaʻO EML4-Alk Fusion ke kumana a me ke kumu no ke alakaʻiʻana i ka hoʻohanaʻana i nā lāʻau lapaʻau.
Kauwe
Ka ha | Wahi a ka BURFER 1, 2 |
VIC (hex) | ʻO ka hopena o keʻano 2 |
Nā poʻoaʻenehana
Huanui | ≤-18 ℃ |
'Āmaʻomaʻo | 9 mau mahina |
ʻAno kiko'ī | ʻO ka pākuhiʻo Paraffin-improdded Pathological Possue a iʻole nā'āpana'āpana |
CV | <5.0% |
Ct | ≤38 |
Lolulu | Hiki i kēia pahu keʻike i nā mutations fuman e like me 20 kope. |
Nā mea pili: | Noi biosysteystems 7500 mau'ōnaehana PCR Noi biosystems 7500 wikiwiki mau'ōnaehana PCR Salan ®-96th Real-Time Gystems ʻO ka helu ottudio ™ 5 mau manawa maoli ʻO Lightcycler®480 Reass-Time Systems PCR Linegene 9600 a me ka'ōnaehanaʻo PCR maoli Ma-6000 maoli-manawa nui ka manawa nui Biorad CFX96 Nā Kūlana Kūlana Lacr Biorad CFX OPus 96 Reass PCR System |
Nā kahe o ka hana
Hoʻonohonohoʻia ka uku uku: Rneasy Ffpe Kit (73504) e Qiagen Builcach (DP439) e T.D39)