Runay ros1 fusion gene mutation
Hua waihona
Hwts-tm009-kanaka rus1 fusion gene stication demation decial decial decle cart (fluorescence pcr)
HAAKAANA
CE
Epideminey
ʻO Ros1 kahi transmembrane tyrosine kinase o kaʻohana insulin. Ua hōʻoiaʻiaʻo Ros1 Fusion Genent e like me ka mea nui o ka hoʻokele kaʻa kaʻa kaʻa liʻiliʻi. Keʻano o kahiʻelele o kahi molekine hou hou,ʻo ka uluʻana o Ros1 Fusion General i nā mea e pili ana i ka 1%. Ma hope o 36%. Ezr, slc34a2, a me SDC4, e hoʻomau mau ia e ho'ōla i ka'āinaʻo Ros1 Tyrostine Kinase. Hiki ke hanaʻiaʻo Ron1 Kinase i ka hōʻailona hōʻailona inoa e like me nā mea e like me nā mea e like me ka gum. Ma waena o Ros1 Fusion Susion, CD74-Rosescount no ka 42%, nā moʻokāki SDC4 no kahi o 12%, a me nā moʻokāki SDC3. Ua hōʻikeʻo Studies i ka pūnaewele ATP-Binding o ka Pata Catalytic Datain o Ros1 Kinase a me ka ATP-Brerostine Kinase I ka mālamaʻana iā NSCLC me Fusion Motion of Ros1. No laila,ʻo ka nānāʻana o Rosatist Fusion Muttications ka Preminos a kumu no ke alakaʻiʻana i ka hoʻohanaʻana i ka hoʻohanaʻana i nā lāʻau CIIRITINI.
Kauwe
Ka ha | Wahi a Bufe 1, 2, 3 a me 4 |
VIC (hex) | ʻO ka helu helu 4 |
Nā poʻoaʻenehana
Huanui | ≤-18 ℃ |
'Āmaʻomaʻo | 9 mau mahina |
ʻAno kiko'ī | ʻO nā kiʻi paraffin-impbelin |
CV | <5.0% |
Ct | ≤38 |
Lolulu | Hiki i kēia pahu keʻike i nā mutations fuman e like me 20 kope. |
Nā mea pili: | Noi biosysteystems 7500 mau'ōnaehana PCRNoi biosystems 7500 wikiwiki mau'ōnaehana PCR Salan ®-96th Real-Time Gystems ʻO ka helu ottudio ™ 5 mau manawa maoli ʻO Lightcycler®480 Reass-Time Systems PCR Linegene 9600 a me ka'ōnaehanaʻo PCR maoli Ma-6000 maoli-manawa nui ka manawa nui Biorad CFX96 Nā Kūlana Kūlana Lacr Biorad CFX OPus 96 Reass PCR System |
Nā kahe o ka hana
Hoʻonohonohoʻia ka uku uku: Rneasy Ffpe Kit (73504) mai Qiagen Bio imp (DP439) mai TIANGEN CHITE.