ʻO ke kanaka TEL-AML1 Fusion Gene Mutation
Inoa mea kūʻai
HWTS-TM016 Kanaka TEL-AML1 Fusion Gene Mutation Detection Kit (Fluorescence PCR)
Epidemiology
ʻO ka maʻi leukemia lymphoblastic acute (ALL) ka maʻi maʻi maʻamau i ka wā kamaliʻi.I nā makahiki i hala iho nei, ua hoʻololi ʻia ka maʻi leukemia acute (AL) mai ke ʻano MIC (morphology, immunology, cytogenetics) i ke ʻano MICM (hoʻohui i ka hoʻāʻo ʻana o ka biology molecular).I ka makahiki 1994, ua ʻike ʻia ʻo ka hui ʻana o TEL i ka wā kamaliʻi ma muli o ka nonrandom chromosomal translocation t(12;21)(p13;q22) ma B-lineage acute lymphoblastic leukemia (ALL).Mai ka loaʻa ʻana mai o ka gene fusion AML1, ʻo ka TEL-AML1 fusion gene ke ala maikaʻi loa e hoʻoholo ai i ka wānana o nā keiki me ka maʻi leukemia lymphoblastic acute.
Kanal
| FAM | TEL-AML1 fusion gene |
| ROX | Hoomalu Kuloko |
Nā ʻāpana ʻenehana
| Waihona | ≤-18 ℃ |
| Kau-ola | 9 mahina |
| ʻAno Hoʻohālike | hāpana iwi iwi |
| Ct | ≤40 |
| CV | <5.0% |
| LoD | 1000 kope/mL |
| kikoo | ʻAʻohe ʻano hoʻololi ʻokoʻa ma waena o nā kits a me nā genes fusion ʻē aʻe e like me BCR-ABL, E2A-PBX1, MLL-AF4, AML1-ETO, PML-RARa fusion genes. |
| Nā mea hana pili | Hoʻohana ʻia Biosystems 7500 Pūnaehana PCR manawa maoli Hoʻohana ʻia ʻo Biosystems 7500 Fast Real-Time PCR Systems QuantStudio®5 Pūnaehana PCR Manawa maoli SLAN-96P Pūnaehana PCR Manawa maoli LightCycler®480 Pūnaehana PCR manawa maoli LineGene 9600 Plus Pūnaehana ʻike PCR manawa maoli MA-6000 ʻOiaʻiʻo ka nui o ka wela wela BioRad CFX96 Pūnaehana PCR Manawa maoli BioRad CFX Opus 96 Pūnaehana PCR Manawa maoli |
Holo Hana
RNAprep Koko Maʻemaʻe Hui Pū ʻIa RNA Extraction Kit (DP433).
