Kanaka cyp2c19 wahine polymorphom

ʻO Cyp2c19 kekahi o nā mea waiwai nui o ka lāʻau lapaʻau nui e pili ana i nā enzymes ma kaʻohana cyp450. He nui nā mea e pau ai ka hopena o nā mea kanu a me 2% o nā lāʻau lapaʻau clinical e cyp2c19 Pili nā lāʻau lapaʻau. ʻO kēia mau hiʻohiʻona nui o * 2 (Rs42444285) a me * 3 (Rs4986893. Keʻena aupuni. * 17 (RS12248560) hiki ke hoʻonui i ka hana enzyme e hoʻohuiʻia e ka cyp2c19 a hoʻonui i ka hopena o ka platelet. No nā poʻe me ka moe kolohe o nā lāʻau lapaʻau, e lawe ana i nā hana maʻamau no ka hanaʻino, etc., hiki ke alakaʻi i ka make Wahi a nāʻokoʻa pilikino i loko o ka metabolism intabolism, ua hoʻokaʻawaleʻia ia iʻehā mau phenotyposism ), ma waena o ka metabolism (im, * 1 / * 2, * 1 / * 3), e lohi, * 2 / * 2, * 2 / * 3, * 3 / * 3).